African health sciences
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African health sciences · Dec 2022
Knowledge and its factors associated towards the prevention of COVID-19 among pregnant women in Ethiopia.
COVID-19 is caused by a single-stranded novel coronavirus that severely affects the respiratory system. The first human COVID-19 was reported in Wuhan city, China, in December 2019. Closing the gap and enhancing knowledge of pregnant women on COVID-19 prevention methods is crucial. However, the studies conducted in Ethiopia were inconsistent and non-conclusive. So, this review aimed to estimate the pooled knowledge prevalence on prevention of COVID 19 and factors associated among pregnant women in Ethiopia. ⋯ This systemic review showed that only half of the pregnant women in Ethiopia had good knowledge about COVID-19, and urban residence was significantly associated with knowledge towards the prevention of COVID-19 among pregnant women in this review. So, the responsible body better strengthen their awareness creation among rural residents and old-age pregnant women.
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African health sciences · Dec 2022
The effectiveness of locally-prepared peritoneal dialysate in the management of children with acute kidney injury in a south-east Nigerian tertiary hospital.
Peritoneal dialysis (PD) is the preferred mode of renal replacement therapy (RRT) in children with acute kidney injury (AKI). The gold standard remains the use of commercially-prepared PD fluid. In resource-poor nations, its availability and affordability remain a challenge. ⋯ PD with locally-prepared dialysate is safe, effective and a life-saving alternative in the management of AKI in children.
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African health sciences · Dec 2022
Evaluation of potential drug-drug interactions and polypharmacy in hospitalized COVID-19 patients.
Drugs that are used in COVID-19 infection, may interact with each other, as well as with the drugs for comorbidities, used concomitantly with COVID-19 treatment. ⋯ Clinically important pDDIs are common among COVID-19 patients and the majority of pDDIs require monitoring of therapy. COVID-19 patients should be closely observed for QT prolongation, hypoglycemia, and hemorrhage due to pDDIs during treatment.
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African health sciences · Dec 2022
Rs7537605 polymorphism in VAV3 gene and rs28665122 polymorphism in SEPS gene are not associated with Hashimoto's thyroiditis in North-East Algerian population.
Hashimoto's thyroiditis (HT) is the most common form of autoimmune thyroid disease which leads, in most cases, to hypothyroidism. HT is also classified as a multifactorial disease, which is caused by an interaction between genetic and environmental factors. Current knowledge of HT genetics is still very limited, especially in Algerian population. ⋯ This is the first genetic study that investigated the genetic association of rs7537605 and rs28665122 inside VAV3 and SEPS genes in Algerian population. Our results suggest that these two SNPs may not be involved in the pathogeneses of HT since we found no association between them and HT/TPOAb levels. Further research that will include larger sample size is required.
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African health sciences · Dec 2022
Knowledge and perceptions about non-communicable diseases by people living with HIV: a descriptive cross-sectional study from Chitungwiza Central Hospital Zimbabwe.
Sub-Saharan Africa has shown a rise in morbidity and mortality due to NCDs. PLHIV have shown to be more exposed to NCDs and identifying the knowledge gaps might help the management of NCDs in PLHIV. ⋯ Knowledge and perception were moderately high, but reduced with decreasing levels of education and increasing age. The study recommends educational campaigns to disseminate information about NCDs in PLHIV, targeting the least educated population groups and those older than 40 years of age.