African health sciences
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African health sciences · Mar 2023
Human herpesvirus-8 infection in Tunisian adult acute leukemia patients.
Human herpesvirus 8 (HHV-8) has been linked to the development of Kaposi's sarcoma (KS)and multiple other hematologic malignant disorders. However, the role of HHV-8 in acute leukemia patients is unknown. ⋯ The seroprevalence of HHV-8 infection in Tunisian adult acute leukemia patients was three times as high compared to healthy blood donors, suggesting that patients with acute leukemia might be at increased risk of HHV-8 infection.
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African health sciences · Mar 2023
Clinicopathological, immunohistochemical, molecular-genetic and risk profiles of gastrointestinal stromal tumors in a cohort of Sudanese patients.
Determining the risk of malignant behaviour and mutational status of gastrointestinal stromal tumours (GISTs) guide the management decision and allow optimal individualized patient treatment. ⋯ Sudanese patients with GIST tend to present late. Nearly half of them correspond to the malignant/high-risk category. The frequency of KIT mutations (79.31%) is in line with the literature.
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African health sciences · Mar 2023
Investigation of antiviral substances in Covid 19 by Molecular Docking: In Silico Study.
This paper aimed to investigate the antiviral drugs against Sars-Cov-2 main protease (MPro) using in silico methods. ⋯ Bictegravir, remdevisir and lopinavir drugs showed very good results compared to the N3 inhibitor. Therefore, they could be inhibitory in the Sars Cov-2 Mpro target.
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African health sciences · Mar 2023
Case control study of CD4 cell count and some haematological parameters among hepatitis and non-hepatitis B patients in Oyo State, South-west, Nigeria.
Hepatitis B virus HBV infection is a major cause of chronic liver disease worldwide. CD4 count and haematological parameters (HPs) could be used to monitor the health status of hepatitis B (HB) individuals. This study aimed at assessing levels of CD4 count and some HPs among sufferers of HB patients and controls. ⋯ There were no significant differences between the values of the CD4 count and hematological parameters among HB subjects in this study. There is need for future studies to detect changes in CD4 count and other HPs in HB patients to increase options of screening for immunological changes during management.
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African health sciences · Mar 2023
Experiences of mental health problems vulnerability, psychological symptoms and coping mechanisms of displaced adolescents in North-east Nigeria.
At a global level the issue of forcible internal displacement appears to be somewhat growing. Most internally displaced persons in Nigeria are children and adolescents, but most of the existing literature and public debate focus on the experiences and outcomes of displaced adults. ⋯ Internally displaced adolescents' experience of psychological symptoms and choice of coping mechanisms relate to their contextually perceived needs. Psychosocial support for these adolescents is recommended.