African health sciences
-
African health sciences · Jun 2023
Clinical study on combined "lanzhou prescription" for the treatment of "syndrome of heat-toxin congestion and excessiveness" in children with acute aplastic anemias.
The clinical efficacy of "Lanzhou prescription" plus or minus combined with western medicine in the treatment of children with acute aplastic anemia, 'excessive accumulation of heat toxin', was comprehensively and objectively evaluated. ⋯ Compared with immunosuppressive therapy, lanzhou prescription plus or minus combined with immunosuppressive therapy can alleviate the clinical symptoms and signs of children more effectively, obviously improve the Traditional Chinese Medicine symptoms of children, and help bone marrow hematopoietic stem cells gradually restore hematopoietic function.
-
African health sciences · Jun 2023
Risk factors for pancreatitis occurrence after gallstone treatment using endoscopic retrograde cholangiopancreatography.
Patients with gallstones are prone to pancreatitis after treatment using endoscopic retrograde cholangiopancreatography (ERCP). The aim of this study was to explore the risk factors for pancreatitis occurrence after gallstone treatment using ERCP. ⋯ Patients with gallstones have a higher risk of developing pancreatitis. Young age, long course of disease, gallbladder wall thickness >3 mm, sand-like stones, history of pancreatic disease, pancreatic duct visualization and number of intubation ≥2 are risk factors for post-ERCP pancreatitis.
-
African health sciences · Jun 2023
The practice of using repurposed medications as chemoprophylaxis for COVID-19 by healthcare workers in a tertiary hospital in Southern Nigeria.
Coronavirus disease 2019 (COVID-19) is a viral infection that has been reported in virtually every country. Healthcare workers (HCW) are more at risk of COVID-19 than the general population making them a priority group for vaccination. Before the roll out of COVID-19 vaccines in Nigeria, some HCW were using some repurposed, unapproved drugs to possibly prevent the disease. This study evaluated the frequency and pattern of drug use for COVID-19 prevention. ⋯ Several HCW in Nigeria take drugs to possibly prevent COVID-19. These medications may not offer significant protection against COVID-19. There is an urgent need to increase uptake of COVID-19 vaccines in HCW in Nigeria.
-
African health sciences · Jun 2023
Biological parameters determining the effectiveness of monitoring of HIV / AIDS infected patients in Morocco.
Human Immunodeficiency Virus (HIV) remains one of the world's most serious health challenges. The development of therapeutic regimens has significantly increased survival and reduced HIV-associated morbidities in HIV-infected individuals. However, some people living with HIV may not respond as expected, resulting in treatment failure. The objective of this study is to identify and characterize, by immunological (T-cell CD4) and virological (viral load) parameters, HIV infected patients with therapeutic failure in Morocco. ⋯ In our study, we showed a therapeutic failure rate of 18.2% in HIV-infected patients under treatment in Marrakech region. These failures were mainly related to poor adherence and low CD4+ rates at the initiation of treatment. We concluded that immunological monitoring alone is insufficient to predict virological suppression and therapeutic success. Consequently, we recommend the HIV plasma viral load test be accessible as a routine exam.
-
African health sciences · Jun 2023
Associations of blood glucose, helper T cells and cytokine levels with degree of periodontal lesion in type 2 diabetes mellitus patients accompanied by chronic periodontitis.
To explore the associations of blood glucose with degree of periodontal lesions in patients with type 2 diabetes mellitus (T2DM) accompanied by chronic periodontitis (CP). ⋯ High levels of FPG, HbA1c, IFN-γ and IL-17 are independent risk factors for T2DM accompanied by CP.