African health sciences
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Human coronaviruses (HCoVs) are one of the most common causes of the "common cold". Some HCoV strains, however, can cause fatal respiratory disease. Some examples of these diseases are severe acute respiratory syndrome (SARS), Middle East respiratory syndrome (MERS), and Coronavirus Disease 19 (COVID-19). This article will review the etiology, clinical features, diagnosis, and management of HCoVs. ⋯ Due to the frequency of recombination events and the subsequent emergence of novel strains, HCoVs are becoming more prevalent, making them a global health concern as they can lead to epidemics and pandemics. Understanding the epidemiology, etiology, clinical features, diagnosis, and management of HCoVs is important, especially during this worldwide pandemic.
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African health sciences · Mar 2021
Intra-tumoral distribution of Ki-67 and Cyclin D1 in ER+ mammary carcinoma: quantitative evaluation.
In spite of the strong evidence demonstrating the role of overexpression of Ki-67 and Cyclin D1 markers in breast carcinomas, clinical and pathological data remain to be discussed. This can be explained partly by intratumor heterogeneity. ⋯ In this study, we have adopted a strictly quantitative approach to evaluate and demonstrate intratumor heterogeneity. This establishes one of the main factors for poor response to cancer therapy. To achieve this, intratumor heterogeneity should be usually definable and quantifiable but this domain awaits future progress and methods need to move towards a better understanding of molecular and cellular mechanisms that initiate and maintain this tumor heterogeneity.
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African health sciences · Mar 2021
Comparative StudyComparison of heart rate response and heart rate recovery after step test among smoker and non-smoker athletes.
Exercise performance depend on the ability of the cardiovascular system to respond to a wide range of metabolic demands and physical exertion. ⋯ Smoking was found to affect athletes' cardiovascular fitness. The change of the athletes' heart rate recovery and recovery time contributes to the adaptation of cardiovascular function in training requirements.
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African health sciences · Mar 2021
Hysterosalpingography: a potential alternative to laparoscopy in the evaluation of tubal obstruction in infertile patients?
Evaluation of the fallopian tubes are important for infertile patients. The two most important diagnostic procedures used to evaluate tubal patency are hysterosalpingography and laparoscopy. ⋯ Patients with suspected tubal infertility can primarily be examined using hysterosalpingography in consideration of the invasive nature and the higher complication rate of laparoscopy.
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African health sciences · Mar 2021
Why do married women procure abortion? Experiences from Ile-Ife, south western Nigeria.
In Nigeria, about 1.25million induced abortions occur annually and the country accounts for one-fifth of abortion-related deaths globally. ⋯ Induced abortion still occur among married women particularly those not using contraceptives, aged ≥40 years and those with high parity. More emphasis should be placed on making contraceptives more accessible to married women.