African health sciences
-
African health sciences · Sep 2019
Comparison of sensitivity of bacteria isolated in odontogenic infections to ceftriaxone and amoxicillin-clavulanate.
Odontogenic infections is a cause of mortality and morbidity in maxillofacial patients. This is largely due to resistance of organisms to antibiotics prescribed. ⋯ Out of a total 55 samples taken for bacteriology, 42 (76.4%) yielded positive culture for bacteria. A total number of 21 bacteria species were identified from the positive cultures. Overall, 52% of isolated organisms were sensitive to amoxicillin-clavulanate, 70% were sensitive to Ceftriaxone while 24% were resistant to both antibiotics (Table 3). Ceftriaxone was statistically significantly more potent in inhibiting bacteria growth than amoxicillin-clavulanate (P =0.009). [Table: see text].
-
African health sciences · Sep 2019
Acute human cytomegalovirus infection among voluntary blood donors in the Lake Victoria zone blood transfusion centre: should it be considered in screening?
Despite blood transfusion being a lifesaving option, it may be associated with blood borne infections including human cytomegalovirus(HCMV). The World Health Organization recommends screening of blood products for HCMV before transfusion to pregnant women, neonates and immunocompromised patients. However, this is not routinely practised in many resource limited countries. ⋯ One out 10 blood donors in the Lake Victoria zone blood transfusion centre is acutely infected with HCMV. There is a need to consider screening of HCMV before blood transfusion particularly in resource limited countries where HCMV is endemic.
-
African health sciences · Sep 2019
Prevalence and determinant factors of hookworm infection among school age children in Jawe district, NorthWest Ethiopia.
Hookworm infection is a common parasitic infection in sub-Saharan Africa. The prevalence of hookworm infection is influenced by different determinant factors. This study aimed to determine the prevalence of hookworm infection and determinant factors among school age children in North West Ethiopia. ⋯ The prevalence of hookworm infection was high among school age children. Walking with bare foot, hand washing habit, and absence of proper latrine utilization are the major determinant factors for the high prevalence of hookworm infection. Therefore, community mobilization and health education should be done to decrease hookworm infection among school age children in Jawe district.
-
African health sciences · Sep 2019
Association between the UBE2Z rs46522 and TCF7L2 rs7903146 polymorphisms with type 2 diabetes in south western Iran.
Transcription factor 7-like 2 Protein (TCF7L2) has a strong role in the pathogenesis of type 2 diabetes mellitus (T2DM). Association between rs7903146 and T2D risk reported in some of populations. Also many loci such as UBE2Z rs46522 are affecting by TCF7L2 transcription factor have been found associated with T2D. The present study aimed to evaluate association of the SNPs with risk of T2D among our population. ⋯ Our study indicates no association of T2D in south western Iran with the rs7903146 and rs46522 variants.
-
African health sciences · Sep 2019
Isolation of Janthinobacterium lividum from early onset neonatal sepsis patients in Malaysia.
The term early onset neonatal septicaemia (EONS) refers to invasive bacterial infections that primarily involve the blood stream of neonates during the first 3 days of life. Although early onset neonatal septicaemia is relatively uncommon, it may be associated with case fatality rates of 15-30% and substantial morbidity in surviving infants. ⋯ This study demonstrates the value of PCR in detecting bacteria where special growth requirement is involved.