African health sciences
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African health sciences · Sep 2023
Assessment of the relationship between miR-499C/T (rs3746444) polymorphism and lung carcinoma in Iranian population; a case-control study.
Lung carcinoma is characterized by uncontrollable division of respiratory system cells with detrimental and lethal consequences on human health. Critical roles of microRNAs (miR) are scientifically approved in biological and pathological pathways, such as the role of miR-499 (rs3746444) in lung carcinomas. Thus, in this case-control investigation, we aimed to assess the probable relationship between miR-499C/T variant and the occurrence of lung carcinoma in Iranian population for the first time. ⋯ In this study, a possible relationship among miR-499C/T polymorphism and lung carcinoma was detected in Iranian population. Since this study was conducted for the first time, thus other supplementary assessments are needed for definite conclusion.
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African health sciences · Sep 2023
Correlations of intestinal microorganisms with liver and immune functions of patients with human immunodeficiency virus and hepatitis B virus coinfection.
Human immunodeficiency virus (HIV) and hepatitis B virus (HBV) coinfection has threatened the survival of HIV-infected people. To explore the correlations of intestinal microorganisms with liver and immune functions of patients with HIV/HBV coinfection. ⋯ HIV aggravates the liver damage and immuno-inflammatory response in HBV patients.
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African health sciences · Sep 2023
Observational StudyClinical value of CVP+VIVC in predicting fluid resuscitation in patients with septic shock.
To explore the clinical value of central venous pressure (CVP) + inferior vena cava respiratory variability (VIVC) in fluid resuscitation in spontaneously breathing patients with septic shock. ⋯ Combination of CVP and VIVC may have a good effect on the evaluation of volume responsiveness in patients with septic shock, which is better than single CVP and VIVC. Combination of CVP and VIVC can be adopted to predict fluid responsiveness volume responsiveness in septic shock patients, which is of great significance for guiding clinical fluid responsiveness therapy.
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African health sciences · Sep 2023
Neutralising antibodies against SARS-CoV-2 give important information on Covid-19 epidemic evolution in Rabat, Morocco, March 2020-February 2021.
The SARS-CoV-2 is an extremely contagious and acute viral disease mainly affecting humans. ⋯ And increase of NAbs was observed over time and correlated with the post-epidemic waves of COVID-19 in Morocco.
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African health sciences · Sep 2023
mHealth app usage amongst paediatric department doctors in South Africa.
Smartphone and mobile health (mHealth) applications (apps) have become an integral part of the day-to-day function of healthcare professionals, allowing quick, comprehensive, and up-to-date access to current clinical guidelines and other reference material. ⋯ Medical apps are frequently used among paediatric medical doctors of all ranks. Drug dosing, diagnostic and clinical decision-making apps are the most common app categories in use. Improved awareness of the regulations pertaining to the use of mHealth apps amongst doctors is required.