African health sciences
-
African health sciences · Dec 2022
Rs7537605 polymorphism in VAV3 gene and rs28665122 polymorphism in SEPS gene are not associated with Hashimoto's thyroiditis in North-East Algerian population.
Hashimoto's thyroiditis (HT) is the most common form of autoimmune thyroid disease which leads, in most cases, to hypothyroidism. HT is also classified as a multifactorial disease, which is caused by an interaction between genetic and environmental factors. Current knowledge of HT genetics is still very limited, especially in Algerian population. ⋯ This is the first genetic study that investigated the genetic association of rs7537605 and rs28665122 inside VAV3 and SEPS genes in Algerian population. Our results suggest that these two SNPs may not be involved in the pathogeneses of HT since we found no association between them and HT/TPOAb levels. Further research that will include larger sample size is required.
-
African health sciences · Dec 2022
Experiences of LGBTI+ individuals in accessing right to health; a survey study from Turkey.
In Turkey, LGBTI+s is experiencing discrimination in all areas of their lives. ⋯ The knowledge and attitude of healthcare professionals are one of the essential determinants of LGBTI+s' use of their right to health. Alienating and homophobic behaviors against LGBTI+s is the biggest problem for LGBTI+s to receive quality health care in Turkey.
-
African health sciences · Dec 2022
MicroRNA-186 suppresses cell proliferation and metastasis in bladder cancer.
Bladder cancer (BCa) is a common malignancy in the urinary system. This study aims to explore the role of miR-186 in BCa tumorigenesis. ⋯ miR-186 has the potential to be used as a biomarker in the early detection of BCa.
-
Pneumothorax is a rare but recognized cause of respiratory distress in the newborn. It can occur spontaneously or post-traumatic. We report our experience in a term male neonate who had primary spontaneous pneumothorax. He had no surgical intervention but completely recovered with conservative management and supplemental oxygen.
-
African health sciences · Dec 2022
Discontinuation of contraceptives among adolescent girls aged 15-19 years in Nigeria: a descriptive analysis.
Adolescent girls are the mostly affected with maternal and child complications. Contraceptive use is an important tool in curbing sexual and reproductive health challenges especially among adolescent girls in the developing countries. Despite, the low use of contraceptives among adolescents in Nigeria, the possibility of discontinuation of use after initiation is strong. ⋯ One in five of unmarried adolescents who ever use a method, discontinue use because of sexual frequency and type of method used.