Medicina clinica
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Letter Case Reports
Albumin as a prognostic marker in the percutaneous aortic valve replacement.
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In recent years, immunotherapy has become an important pillar of cancer treatment, with high response rates regardless of tumour histology or baseline mutations. However, immune activation associated with check-point inhibitors is not selective and a large variety of immune-related adverse events have been associated with anti-PD1, anti-PD-1/L-1 and anti-CTLA-4 agents. Though diagnosis and treatment of these toxicities have been established according to the recommendations from clinical trials and in line with the autoimmune disorders that they mimic, increasing real-world data is coming up showing that these adverse events may have differential characteristics and management, especially in terms of the use of corticoids, second-line treatments, salvage therapy for life-threatening cases and reintroduction of immunotherapy. Herein we present a comprehensive review of current recommendations and real-world data on the main immune-related adverse events of immunotherapy.
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Case Reports
Properties of a scale of concern for COVID-19: Exploratory analysis in a Peruvian sample.
Concern about getting sick could help prevent disease. The aim of this study was to analyze the psychometric properties of a COVID-19 concern scale (EPCov-19). ⋯ This is a valid and reliable instrument for measuring concern about the spread of COVID-19 and can be used in future studies.