Journal of the Chinese Medical Association : JCMA
The most recent articles from:
J Chin Med Assoc
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Randomized Controlled Trial
Effect of the infusion rate of propofol on the onset time of rocuronium.
Administration of propofol, especially rapid administration, decreases patient cardiac output (CO) to various degrees. CO might influence the buildup of an effective drug level within the neuromuscular junction and affect the onset time of neuromuscular blockers. The present study aimed to investigate the effects of different infusion rates of propofol on patient CO and the onset time of rocuronium. ⋯ Rapid administration of propofol significantly delays the onset time of rocuronium by altering CO as measured with the Finometer monitor.