Chinese medical journal
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Chinese medical journal · Oct 2011
Clinical significance of chromosomal abnormalities detected by interphase fluorescence in situ hybridization in newly diagnosed multiple myeloma patients.
Chromosome 13q14 deletion (del13q14), chromosome 1q21 gain (amp1q21) and chromosome 17p13 deletion (del17p13) are the most frequent chromosomal aberrations in multiple myeloma (MM). They play an important role in prognosis. The aim of this study was to investigate the clinical significance of the chromosomal changes in Chinese MM patients. ⋯ The prevalence of chromosomal abnormalities of MM patients was similar in Chinese and Caucasian people. Genetic changes were associated with patients' responses to therapies and prognosis.
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Chinese medical journal · Oct 2011
ReviewTranslational research and its effects on medicine in China.
Translational research has become a globally recognized model of medical research. Chinese government and doctors have begun to discuss the plan for its development. ⋯ In this essay, the authors discuss the disadvantages of translational research, its effects on clinical work and medical education, highlighting some potential problems and risks in theory and practice on case basis. Some important research management requirements are summarized in this essay to help bring the therapy from the research laboratory to the patient's bedside.
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Chinese medical journal · Oct 2011
Randomized Controlled Trial Multicenter StudyDuloxetine versus placebo in the treatment of patients with generalized anxiety disorder in China.
Duloxetine is approved for the treatment of generalized anxiety disorder (GAD) in the United States and elsewhere. This study aimed to assess the efficacy, tolerability, and safety of duloxetine in Chinese patients with GAD. ⋯ Duloxetine 60 - 120 mg once daily is effective and well-tolerated for the treatment of patients with GAD in China.
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Chinese medical journal · Oct 2011
Multicenter StudyReal world clinical performance of the zotarolimus eluting coronary stent system in Chinese patients: a prospective, multicenter registry study.
Early clinical trials with the Endeavor zotarolimus eluting stent (ZES) in western populations demonstrated low rates of target lesion revascularization with a favorable safety profile including low late stent thrombosis with up to 5 years of follow-up. The aim of this clinical registry study was to evaluate real world clinical performance of the ZES coronary system in Chinese patients. ⋯ Mid-term results from the real-world China Endeavor Registry suggest that Endeavor ZES was safe and effective in Chinese patients.
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Chinese medical journal · Oct 2011
Case ReportsAesthetic fingertip reconstruction with partial second toe transfer.
Fingertip defect significantly affects the appearance of the hand. The aim of this research was to evaluate the clinical effect of aesthetic fingertip reconstruction with partial second toe transfer. ⋯ Partial second toe transfer is an ideal aesthetic reconstruction method for fingertip defects; it can not only achieve a satisfactory appearance of the fingertip, but can also obtain excellent sensory and motor functions.