Chinese medical journal
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Chinese medical journal · Jul 2013
Clinicopathological significance of altered metallothionein 2A expression in gastric cancer according to Lauren's classification.
Dysregulated metallothionein 2A (MT2A) has been implicated in carcinogenesis. The purpose of this study was to investigate the expression of MT2A in gastric cancer (GC) and its correlation with prognosis. ⋯ Expression status of MT2A might be a useful prognostic biomarker for GC, especially when used in combination with Lauren's classification.
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Chinese medical journal · Jul 2013
Comparative StudyComparative outcomes between cord blood transplantation and bone marrow or peripheral blood stem cell transplantation from unrelated donors in patients with hematologic malignancies: a single-institute analysis.
Umbilical cord blood (UCB) has grown substantially as an alternative source of hematopoietic stem cells for unrelated donor transplantation in both adult and pediatric patients. Our aim was to assess the leukemia-free survival (LFS) and some primary results, such as hematologic recovery, risk of graft-versus-host disease (GVHD), relapse, and long-term survival, after unrelated cord blood transplantation compared with the outcomes of transplantations from other unrelated graft source. ⋯ These data support the use of UCB donors as an alternative allogeneic donor.
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Chinese medical journal · Jul 2013
Initial study of magnetic resonance diffusion tensor imaging in brain white matter of early AIDS patients.
HIV is a neurotropic virus which can cause brain white matter demyelination, gliosis, and other pathological changes that appear as HIV encephalitis or AIDS dementia. The purpose of this study was to investigate the change of the diffused condition of water molecules in brain white matter in early acquired immune deficiency syndrome (AIDS) patients using MR diffusion tensor imaging (DTI). ⋯ The diffused changes of water molecules in brain white matter in AIDS patients are related to brain white matter regions. DTI examination can detect the brain white matter lesions early in AIDS patients.