Chinese medical journal
-
Chinese medical journal · Sep 2017
Randomized Controlled TrialEfficacy of Real-world Entecavir Therapy in Treatment-naïve Chronic Hepatitis B Patients.
Entecavir (ETV) has been shown to be effective in randomized controlled trials in highly selected patients with hepatitis B virus (HBV) infection. This study aimed to evaluate the efficacy of ETV in chronic hepatitis B (CHB) patients in the real-world setting. ⋯ ETV treatment was effective for HBV DNA suppression in this study, but HBsAg loss and HBeAg clearance/seroconversion rates were lower compared with previous clinical trials. PVR was associated with HBeAg clearance and cirrhosis.