Chinese medical journal
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Chinese medical journal · May 2019
Meta AnalysisLevosimendan does not reduce the mortality of critically ill adult patients with sepsis and septic shock: a meta-analysis.
Previous studies on whether or not levosimendan improved the prognosis of patients with sepsis and septic shock have been inconsistent. We aimed to provide an updated analysis of the therapeutic value of levosimendan in adult patients with sepsis and septic shock, in order to provide evidence-based medical evidence for its use. ⋯ Based on current clinical evidence, levosimendan does not reduce mortality in adult critically ill patients with sepsis and septic shock. Physicians should use levosimendan with caution in patients with sepsis and septic shock.
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Chinese medical journal · May 2019
Multicenter StudyPredictive accuracy of Sepsis-3 definitions for mortality among adult critically ill patients with suspected infection.
Sepsis-3 definitions have been published recently; however, their diagnostic value remains controversial. This study was to assess the accuracy of Sepsis-3 definitions compared to Sepsis-1 definitions by stratifying mortality among adult critically ill patients with suspected infection. ⋯ In adult critically ill patients with suspected infection, the Sepsis-3 definitions were relatively accurate in stratifying mortality and were superior to the Sepsis-1 definitions.
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Chinese medical journal · May 2019
Multicenter StudyA multi-center cross-sectional study on blood purification among adult patients in intensive care unit in China: a study protocol.
Blood purification (BP) is one of the most important rescue measures for patients with critical illness in the intensive care unit (ICU), especially for those with acute kidney injury. The purpose of this nationwide survey was to reveal the real world of current BP practice in different ICUs all over China. This study was designed to be a multi-center cross-sectional study. ⋯ This nationwide survey may contribute to reveal the real world of current BP practice in different ICUs all over China.
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Chinese medical journal · May 2019
Clinical characteristics of 5375 cases of acute pancreatitis from a single Chinese center, 1996-2015.
Supplemental Digital Content is available in the text
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Chinese medical journal · May 2019
Central venous pressure value can assist in adjusting norepinephrine dosage after the initial resuscitation of septic shock.
New definitions for sepsis and septic shock (Sepsis-3) were published, but the strategy to adjust vasopressors after the initial guidelines is still unclear. We conducted a retrospective observational study to explore dosing strategy of norepinephrine (NE). ⋯ After patients with septic shock (Sepsis-3) resuscitated to reach the initial recovery target goals, combination of CVP and MAP refer to usual levels can help doctors make the next decision to make the correct choice of increase NE dosage or decrease NE dosage.