Cardiovascular revascularization medicine : including molecular interventions
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Cardiovasc Revasc Med · Sep 2014
Meta Analysis Comparative StudyBivalirudin versus heparin for percutaneous coronary intervention: an updated meta-analysis of randomized controlled trials.
Given controversy over anticoagulation regimens for percutaneous coronary intervention (PCI), we performed an updated meta-analysis of randomized controlled trials (RCTs) to compare bivalirudin versus heparin. ⋯ Meta-analysis of 14 RCTs with 30,446 patients demonstrated that bivalirudin is associated with higher risk of stent thrombosis but lower risk of major bleeding compared with heparin.