Clinical and vaccine immunology : CVI

The most recent articles from: Clin. Vaccine Immunol. July 2012

Clin. Vaccine Immunol. · Jul 2012

Comparative Study

Analysis of variola and vaccinia virus neutralization assays for smallpox vaccines.

Possible smallpox reemergence drives research for third-generation vaccines that effectively neutralize variola virus. A comparison of neutralization assays using different substrates, variola and vaccinia (Dryvax and modified vaccinia Ankara [MVA]), showed significantly different 90% neutralization titers; Dryvax underestimated while MVA overestimated variola neutralization. Third-generation vaccines may rely upon neutralization as a correlate of protection.

read more… mark as read…

Want more great medical articles?

Keep up to date with a free trial of metajournal, personalized for your practice.
1,694,794 articles already indexed!