Clinical research in cardiology : official journal of the German Cardiac Society
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Randomized Controlled Trial Multicenter Study
Reduction of inappropriate ICD therapies in patients with primary prevention of sudden cardiac death: DECREASE study.
A significant number of patients with an implantable cardioverter/defibrillator (ICD) for primary prevention receive inappropriate shocks. Previous studies have reported a reduction of inappropriate therapies with simple modifications of ICD detection settings, however, inclusion criteria and settings varied markedly between studies. Our aim was to investigate the effect of raising the ICD detection zone in the entire primary prevention ICD population. ⋯ http://clinicaltrials.gov ; ClinicalTrials.gov identifier NCT01217528.
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To investigate the influence of non-cardiac comorbidities on outcomes of patients enrolled in the German transcatheter mitral valve interventions (TRAMI) registry. ⋯ MitraClip device placement is feasible and safe in patients with multiple non-cardiac comorbidities resulting in a significant clinical improvement and acceptable intrahospital and 30-day event rates. Renal failure is an independent predictor of outcome.