Journal of Nepal Health Research Council
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J Nepal Health Res Counc · Apr 2021
Clinical Outcome of Cooled Radiofrequency Ablation in Chronic Knee Pain Osteoarthritis: An Initial Experience from Nepal.
Cooled Radiofrequency ablation is a newer technique for management of chronic knee pain in osteoarthritis. The aim of the study is to evaluate the clinical outcomes in patients with chronic osteoarthritis in terms of pain scores for first six months of cooled radiofrequency ablation using ultrasound guidance. ⋯ Cooled Radiofrequency using Ultrasound guidance for management of knee pain in chronic osteoarthritis is promising and reduces Numerical Rating Score significantly from baseline at 1 month and 6 months respectively.
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Road traffic accidents is growing continuously as a global burden and would be a leading cause of death in developing countries. The global burden of road traffic accidents continues to grow and promises to overtake tropical diseases as leading causes of death in the developing world. This study aimed to study the pattern and causes of road traffic accidents in Morang district. ⋯ Weekends, evening, highways and two wheelers are more accident prone time, place and vehicles respectively. Overspeed and negligence of driver tends to major cause of accidents and majority of victims are the young bike riders and pedestrians.
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In the race for a safe and effective vaccine against Coronavirus disease-19 manufacturer plays a critical role throughout the development, clinical trial, manufacturing, supply, and vaccination phases. For the efficacy of Coronavirus disease-19 vaccine, proper transport, storage, vaccine carrier, adjuvant, dosage form and route of vaccine administration plays a crucial role for immune response. ⋯ It is urgent to improve health promotion and reduce the barriers to Coronavirus disease-19 vaccination. Keywords: COVID-19; vaccine development; vaccination.
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J Nepal Health Res Counc · Jan 2021
Case ReportsKawasaki Disease like Multisystem Inflammatory Syndrome in a Toddler during SARS-CoV-2 Pandemic in Nepal.
Multisystem inflammatory syndrome in children is a new childhood inflammatory disorder associated with respiratory syndrome coronavirus 2 (SARS-CoV-2). This illness of elevated inflammatory markers and multiple organ involvement similar to Kawasaki disease is not commonly reported from Asia. A 17-month-old boy presented with acute onset fever, rash, non-exudative conjunctivitis and swellings of hands and legs. ⋯ The child responded to treatment with intravenous immunoglobulin and high dose aspirin. Hence, amidst SARS-CoV-2 pandemic, multisystem inflammatory syndrome in children should be suspected and effectively treated even in a country like Nepal. Keywords: Kawasaki disease; multiple inflammatory syndrome in children; Nepal; respiratory syndrome coronavirus 2.
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J Nepal Health Res Counc · Jan 2021
Serum Vitamin D in Patients with Chronic Periodontitis and Healthy Periodontium.
Periodontitis is inflammatory disorder resulting in progressive destruction of the periodontal ligament and alveolar bone with pocket formation, recession, or both. Vitamin D has a benefit in bone metabolism and anti-inflammatory activity involving T-cell homeostasis. The objective of this study was to compare the vitamin D level in patient with chronic periodontitis and healthy periodontium and evaluate its correlation. ⋯ There are no differences in the level of serum vitamin D between healthy and chronic periodontitis groups. No association was seen between vitamin D level and chronic periodontitis.