Journal of Nepal Health Research Council
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J Nepal Health Res Counc · Jan 2012
Randomized Controlled TrialStudy of haemodynamic and endocrine stress responses following carbon dioxide pneumoperitonium.
The aim of the study is to investigate the effect of oral gabapentin or clonidine versus placebo premedication on haemodynamic and endocrine responses in patients of American Society of Anesthesiology (ASA) physical status I and II undergoing laparoscopic cholecystectomy. ⋯ Oral clonidine or gabapentin premedication offers intraoperative haemodynamic stability in laparoscopic cholecystectomy. When serum cortisol is taken as a stress marker, gabapentin group exhibited significant attenuation of stress of PP, p<0.05.