Anesthesiology
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Observational Study
Dynamic Cortical Connectivity during General Anesthesia in Surgical Patients.
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Anesthetic-induced loss of consciousness is accompanied by changes in functional connectivity within and between brain networks. ⋯ Anesthesia-induced alterations of functional connectivity are dynamic despite the stable and prolonged administration of isoflurane, in the absence of any noxious stimuli. Changes in connectivity over time will likely yield more information as a marker or mechanism of surgical anesthesia than any single pattern.
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Randomized Controlled Trial
Nasopharyngeal Tube Effects on Breathing during Sedation for Dental Procedures: A Randomized Controlled Trial.
Dental procedures under sedation can cause hypoxic events and even death. However, the mechanism of such hypoxic events is not well understood. ⋯ Patients under sedation for dental procedure frequently encounter obstructive apnea/hypopnea events. The majority of the obstructive apnea/hypopnea events were not detectable by pulse oximetry. The effectiveness of a small-diameter nasopharyngeal tube to mitigate the events is limited.