Anesthesia and analgesia
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Anesthesia and analgesia · Apr 2007
Comparative StudyThe effect of albumin concentration on plasma sodium and chloride measurements in critically ill patients.
We tested the hypothesis that the difference between indirect and direct sodium assays would be related to the plasma albumin concentration. Further, we proposed that differences between indirect and direct chloride assays might be explained by interference from other plasma constituents, particularly bicarbonate, and possibly albumin. ⋯ The central laboratory and ICUs assays are analytically, statistically, and clinically different for both sodium and chloride. Unless taken into account, the differences could be large enough in hypoalbuminemic populations (such as critically ill patients) to affect clinical diagnosis and decision making.
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Anesthesia and analgesia · Apr 2007
Randomized Controlled TrialThe effect of epidural anesthesia with different concentrations of ropivacaine on sevoflurane requirements.
We evaluated sevoflurane requirements during combined general-epidural anesthesia with different concentration of ropivacaine. ⋯ Epidural anesthesia can decrease sevoflurane requirements to a larger extent when a higher concentration of ropivacaine was applied.
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Anesthesia and analgesia · Apr 2007
Comparative Study Clinical TrialPreoperative ultra short-term entropy predicts arterial blood pressure fluctuation during the induction of anesthesia.
In this study, we sought to determine whether the preoperative nonlinear index of heart rate variability, ultra short-term entropy (UsEn), could predict cardiovascular responses to the induction of general anesthesia. ⋯ UsEn could predict arterial blood pressure fluctuations during the induction of anesthesia.
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Anesthesia and analgesia · Apr 2007
Exploring sociodemographic and personality characteristic predictors of parental pain perceptions.
We studied the relationship between children's and parents' sociodemographic and personality characteristics and parents' perceptions of their children's pain. ⋯ We conclude that many parents have misconceptions of pain and analgesics, and that child and parent personality characteristics can be used to identify parents at risk of these misconceptions.
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Anesthesia and analgesia · Apr 2007
Comparative StudyActivity of the serotonergic system during isoflurane anesthesia.
Microdialysis studies have demonstrated that the release of serotonin (5-hydroxytryptamine, 5-HT) in the serotonergic projection areas increases during waking and decreases during sleep in rat and cat, suggesting that 5-HT plays an important role in modulation of sleep. Although it might be expected that 5-HT release is also decreased during general anesthesia, the functional contribution of serotonergic neurons in pharmacological effects of volatile anesthetics has not been fully investigated. ⋯ It is suggested that a change in the activity of the serotonergic system in the brain is involved in the hypnotic action of isoflurane.