Anesthesia and analgesia
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Anesthesia and analgesia · Sep 2011
Randomized Controlled Trial Comparative StudyThe temperature and humidity in a low-flow anesthesia workstation with and without a heat and moisture exchanger.
The Dräger Primus anesthesia workstation has a built-in hotplate to heat the patient's exhaled gas. The fresh gas flow is mixed with the heated exhaled gas as they pass through the soda lime canister. A heat and moisture exchanger (HME) may also be used to further heat and humidify the inhaled gas. In this study we measured the temperature and humidity of the inhaled gas coming from the Dräger Primus with or without a HME. ⋯ The Primus anesthesia workstation partially humidifies the inspired gas when a low fresh gas flow is used. Insertion of an HME increases the humidity in inhaled gas, bringing it close to physiological values.
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As with other types of research, there are concerns about reporting of survey research in anesthesia journals. We hypothesized that use of survey reporting items would be inconsistent in survey research reported in anesthesia journals. ⋯ Inconsistent reporting may compromise the transparency and reproducibility of survey reports.
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Anesthesia and analgesia · Sep 2011
Randomized Controlled Trial Multicenter Study Comparative StudyA randomized, open-label study of the safety and tolerability of fospropofol for patients requiring intubation and mechanical ventilation in the intensive care unit.
Current drugs for induction and maintenance of sedation in mechanically ventilated patients in the intensive care unit have limitations. Fospropofol, a prodrug of propofol, has not been studied as a sedative in the ICU setting. ⋯ This pilot study suggests that fospropofol, administered in either an infusion/bolus or infusion-only regimen, is tolerable and effective for short-term induction and maintenance of sedation in mechanically ventilated intensive care unit patients.
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Anesthesia and analgesia · Sep 2011
Randomized Controlled Trial Comparative StudyLearning endotracheal intubation using a novel videolaryngoscope improves intubation skills of medical students.
Teaching endotracheal intubation to medical students is a task provided by many academic anesthesia departments. We tested the hypothesis that teaching with a novel videolaryngoscope improves students' intubation skills. ⋯ Education using a video system mounted into a traditional Macintosh blade improves intubation skills in medical students.
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Anesthesia and analgesia · Sep 2011
Randomized Controlled TrialThe effect of altering skin-surface cooling speeds on vasoconstriction and shivering thresholds.
Both core and skin temperatures contribute to steady-state thermoregulatory control. Dynamic thermoregulatory responses trigger aggressive defenses against rapid thermal perturbations. These responses potentially complicate interpretation of thermoregulatory studies and could slow induction of therapeutic hypothermia. We thus tested the hypothesis that rapid external skin-cooling triggers vasoconstriction and shivering at higher mean skin temperatures than slow or moderate rates of skin cooling. ⋯ Onset of vasoconstriction and shivering occurred at similar mean skin temperatures with all 3 cooling rates. Aggressive surface cooling can thus be used in thermoregulatory studies and for induction of therapeutic hypothermia without provoking dynamic thermoregulatory defenses.