European journal of clinical investigation
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Eur. J. Clin. Invest. · Nov 2020
ReviewCIMT as a risk factor for Stroke Subtype: A Systematic Review.
An increase in the common carotid artery intima-media thickness (CCA-IMT) is generally considered an early marker of atherosclerosis and is a well-established predictor of cardiovascular disease (CVD). An association between changes in CCA-IMT and risk of stroke has been reported but has conflicting findings. ⋯ Carotid intima thickness measurements are found to be associated with the risk of stroke along with its subtypes and may be used as a diagnostic marker for predicting the risk of stroke events.
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Eur. J. Clin. Invest. · Nov 2020
ReviewCIMT as a risk factor for Stroke Subtype: A Systematic Review.
An increase in the common carotid artery intima-media thickness (CCA-IMT) is generally considered an early marker of atherosclerosis and is a well-established predictor of cardiovascular disease (CVD). An association between changes in CCA-IMT and risk of stroke has been reported but has conflicting findings. ⋯ Carotid intima thickness measurements are found to be associated with the risk of stroke along with its subtypes and may be used as a diagnostic marker for predicting the risk of stroke events.
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Eur. J. Clin. Invest. · Nov 2020
Review Meta Analysis Comparative StudyEfficacy of various treatment modalities for nCOV-2019: a systematic review and meta-analysis.
Several therapeutic agents have been investigated for treatment of novel coronavirus 2019 (nCOV-2019). We conducted a systematic review and meta-analysis to assess the efficacy of various treatment modalities in nCOV-2019 patients. ⋯ Our meta-analysis suggests that except in vitro studies, no treatment has shown overall favourable outcomes in nCOV-2019 patients. Lopinavir-ritonavir, remdesivir and tocilizumab may have some benefits, while hydroxychloroquine administration may cause harm in nCOV-2019 patients. Results from upcoming large clinical trials may further clarify role of these drugs.
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Eur. J. Clin. Invest. · Nov 2020
Review Meta Analysis Comparative StudyEfficacy of various treatment modalities for nCOV-2019: a systematic review and meta-analysis.
Several therapeutic agents have been investigated for treatment of novel coronavirus 2019 (nCOV-2019). We conducted a systematic review and meta-analysis to assess the efficacy of various treatment modalities in nCOV-2019 patients. ⋯ Our meta-analysis suggests that except in vitro studies, no treatment has shown overall favourable outcomes in nCOV-2019 patients. Lopinavir-ritonavir, remdesivir and tocilizumab may have some benefits, while hydroxychloroquine administration may cause harm in nCOV-2019 patients. Results from upcoming large clinical trials may further clarify role of these drugs.
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Eur. J. Clin. Invest. · Nov 2020
ReviewInvestigating the Capabilities of Information Technologies to support Policymaking in COVID-19 Crisis Management; A Systematic Review and Expert opinions.
Today, numerous countries are fighting to protect themselves against the Covid-19 crisis, while the policymakers are confounded and empty handed in dealing with this chaotic circumstance. The infection and its impacts have made it difficult to make optimal and suitable decisions. New information technologies play significant roles in such critical situations to address and relieve stress during the coronavirus crisis. This article endeavours to recognize the challenges policymakers have typically experienced during pandemic diseases, including Covid-19, and, accordingly, new information technology capabilities to encounter with them. ⋯ The results illustrate that the challenges fall into two categories including; encountering the disease and reducing the results of the disease. Furthermore, Internet of things, cloud computing, machine learning and social networking play the most significant roles to address these challenges.