European journal of clinical investigation
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Eur. J. Clin. Invest. · Aug 2023
Sauna bathing, renal function and chronic kidney disease: cross-sectional and longitudinal findings from the KIHD study.
It is uncertain if passive heat therapies are associated with adverse renal outcomes. We sought to evaluate the cross-sectional and longitudinal associations of the frequency of sauna bathing with renal function measures and chronic kidney disease (CKD). ⋯ Cross-sectional and longitudinal observational evidence suggests that frequent sauna bathing is not associated with impaired renal function or the future risk of CKD.
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Eur. J. Clin. Invest. · Aug 2023
Observational StudyPrognostic role of CRP-independent inflammatory patterns in patients undergoing primary percutaneous interventions.
Despite the key pathophysiological role of inflammation in the development of coronary artery disease (CAD), the evaluation of inflammatory status has not been clearly established in patients presenting with acute coronary syndrome (ACS). The aim of this study is to evaluate the prevalence of CRP-independent inflammatory patterns in patients referred for primary percutaneous coronary intervention (pPCI) and to determine their one-year relationship with adverse clinical outcomes. ⋯ 'Persistent-high' and 'up-sloping' CRP-independent inflammatory patterns in patients undergoing primary PCI are associated with an increased risk of adverse events at one-year follow-up. The prognostic value of these inflammatory patterns might be helpful to individualize potential therapeutic targets.
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Eur. J. Clin. Invest. · Jul 2023
Randomized Controlled TrialAssociation of hydroxytyrosol enriched olive oil with vascular function in chronic coronary disease.
Hydroxytyrosol reduces low-density lipoprotein oxidation, contributing to prevention of atherosclerosis progression. ⋯ Hydroxytyrosol-enriched olive oil may have beneficial effects on endothelial, arterial and LV diastolic function likely by reducing oxidative and inflammatory burden in CCAS, though further studies are needed to confirm this mechanism.
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Eur. J. Clin. Invest. · Jul 2023
Randomized Controlled TrialThe effect of exercise intensity on the inflammatory profile of cancer survivors: A randomised crossover study.
Systemic inflammation has been clearly linked to poorer health outcomes from cancer diagnosis through to survivorship. There is accumulating evidence that exercise can reduce inflammation. However, the optimal intensity of exercise to reduce systemic inflammation is unknown. ⋯ The potential to scale up low-intensity exercise over time is likely to be more broadly applicable and achievable for cancer survivor cohorts while still eliciting beneficial effects on systemic inflammation.