The Medical clinics of North America
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Med. Clin. North Am. · Nov 2002
ReviewBarrett's esophagus and esophageal adenocarcinoma: pathogenesis, diagnosis, and therapy.
Gastric juice that refluxes into the esophagus can injure esophageal squamous epithelium. When the injury heals through a metaplastic process in which an abnormal columnar epithelium replaces the injured squamous one, the resulting condition is called Barrett's esophagus. ⋯ This article examines such issues as the treatment, endoscopic surveillance, and chemoprevention of Barrett's esophagus. Also included are published guidelines and recommendations.