The American journal of drug and alcohol abuse
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Am J Drug Alcohol Abuse · Nov 2012
Comment LetterIntoxication delirium following use of synthetic cathinone derivatives.
In published reports of hallucinatory delirium following use of "bath salts" analytic laboratory testing has demonstrated the synthetic cathinone derivative methylenedioxypyrovalerone (MDPV). MDPV can cause a false-positive screening immunoassay result for phencyclidine (PCP). Patients using MDPV are prone to development of the syndrome of excited delirium (ExD), a condition also described with PCP. ⋯ Patients using MDPV are prone to the development of toxic delirum with some developing ExD. a condition associated with considerable risk for serious medical morbidity. Commonly used interventions directed at extreme agitation and paranoia may exacerbate the pathophysiology of ExD.
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Am J Drug Alcohol Abuse · Nov 2012
Geographic distribution of synthetic cannabinoid exposures reported to Texas poison centers.
Synthetic cannabinoids have recently gained popularity as recreational drugs because they provide a marijuana-like high and cannot be detected in typical urine drug screens. However, the use of synthetic cannabinoids may result in a variety of adverse effects. ⋯ Such information may be useful when attempting to target education and prevention activities.
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Among the novel classes of synthetic "designer" drugs that have become increasingly popular among recreational drug users are synthetic cathinones. There is limited information on exposures to these substances. ⋯ This study adds to the limited information currently available on synthetic cathinone exposures.