Journal of the National Cancer Institute
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J. Natl. Cancer Inst. · Jan 2015
Meta AnalysisMigraine and breast cancer risk: a prospective cohort study and meta-analysis.
The evidence for an association between migraine and breast cancer risk is inconclusive. While female sex hormones have been proposed as one underlying mechanism, data on sex hormone levels in migraineurs are sparse. ⋯ In this large cohort study, migraine was not associated with breast cancer risk or differences in endogenous sex hormone levels. While case-control studies suggest an inverse association between migraine and breast cancer risk, prospective cohort studies do not support an association in pooled analyses.