British journal of clinical pharmacology
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Br J Clin Pharmacol · Mar 2014
Review Meta AnalysisStatin use and risk of kidney cancer: a meta-analysis of observational studies and randomized trials.
Clinical studies have shown that statin use may modify the risk of kidney cancer. However, these studies yielded different results. To quantify the association between statin use and risk of kidney cancer, we performed a detailed meta-analysis of published studies regarding this subject. ⋯ The findings of this meta-analysis suggested that there was no association between statin use and risk of kidney cancer. More studies, especially randomized controlled trials and high quality cohort studies with larger sample size and well controlled confounding factors, are needed to confirm this association in the future.