Medical hypotheses
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Data is presented that indicates that Ischaemic heart disease and Cerebrovascular disease are the result of the deleterious effect caused by driving or travelling in a motor vehicle. Ischaemic heart disease (IHD) Cerebrovascular disease (C/V) also referred to as (stroke) Road accident deaths (RAD).
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Historical Article
Insulin potentiation therapy: a new concept in the management of chronic degenerative disease.
In insulin potentiation therapy the hormone insulin is used as an adjunct in the medical management of the chronic degenerative diseases including malignant neoplasia. In this, the recognized physiological action of insulin--that of increasing cell membrane permeability--is taken advantage of to potentiate the pharmacological actions of medications administered concurrently in the therapy. ⋯ The historical context of insulin potentiation therapy is described, and scientific corroboration for its novel hypotheses is given. Insulin potentiation therapy represents a potentially revolutionary concept in the medical management of diseases and is, in the authors' opinion, deserving of intensive scientific investigation through in vitro and in vivo experimentation and properly conducted human clinical trials in a university teaching hospital setting.
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Permanent injury to the nervous system can occur in a number of ways and lead to profound residual disability. Attempts to restore function are being made by many different groups. They range from prosthetic repair to pharmacological intervention. ⋯ One is proposed. From it a rational set of approaches to the restoration of nervous system function is generated. These are outlined.
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Placebo-controlled studies of effects of monosodium L-glutamate (MSG) and mixed synthetic food dyes in humans which have led to claims that these additives are safe in general use may be questioned on 3 methodological grounds: both active substance and placebo may be inadequately specified in published reports and potent common food allergens are used as placebos.
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Individuals who have a reduced capacity to detoxify cyanide to thiocyanate are at increased risk to experience adverse side effects from laetrile, a cyanide containing substance used in cancer treatment. Since megadoses of ascorbic acid may markedly diminish body stores of cysteine, a sulfur containing amino acid which facilitates the detoxification of cyanide, it is predicted that persons consuming megadoses of ascorbic acid will be at increased risk to experience the adverse side effects from laetrile treatment.