Spine
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Case Reports
Bone graft incorporation in radiographically successful human intervertebral body fusion cages.
Biopsies were obtained from within radiographically successful human intervertebral body fusion cages to document the histology of remodeling bone graft. ⋯ Autogenous bone graft was incorporated in these radiographically successful human intervertebral body fusion cages. A few debris particles were observed, but there was no histologic evidence of particle-induced bone resorption or inflammation.
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A questionnaire survey. ⋯ The use of methylprednisolone in the treatment of acute traumatic spinal cord injury is still controversial. It would appear from a recent prospective audit at the authors' spinal injuries unit that a large percentage of patients in the United Kingdom are not receiving methylprednisolone. Because so much doubt exists, the NASCIS studies should be repeated.
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Randomized Controlled Trial Clinical Trial
Cost effectiveness of periradicular infiltration for sciatica: subgroup analysis of a randomized controlled trial.
A subgroup analysis of a prospective, randomized controlled trial was performed. ⋯ In addition to short-term effectiveness for contained herniations and lesions at L3-L4-L5, steroid treatment also prevented surgery for contained herniations. However, steroid was countereffective for extrusions. The results of the subgroup analyses call for a verification study.
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Randomized Controlled Trial Multicenter Study Comparative Study Clinical Trial
2001 Volvo Award Winner in Clinical Studies: Lumbar fusion versus nonsurgical treatment for chronic low back pain: a multicenter randomized controlled trial from the Swedish Lumbar Spine Study Group.
A randomized controlled multicenter study with a 2-year follow-up by an independent observer. ⋯ Lumbar fusion in a well-informed and selected group of patients with severe CLBP can diminish pain and decrease disability more efficiently than commonly used nonsurgical treatment.
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Axial load-dependent changes in the lumbar spine of supine healthy volunteers were examined using a compression device compatible with magnetic resonance imaging. ⋯ The axial force of 50% body weight in supine posture simulates the upright lumbar spine morphologically. No change in intervertebral angle occurred at L4-L5. However, disc height at L4-L5 decreased significantly during compression.