Spine
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Randomized Controlled Trial Clinical Trial
Randomized controlled trial of neural mobilization after spinal surgery.
Randomized controlled trial with 12-month follow-up. ⋯ The neural mobilization protocol evaluated in this study did not provide an additional benefit to standard postoperative care for patients undergoing spinal surgery. The authors advocate that this protocol not be used in clinical practice.
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Randomized Controlled Trial Multicenter Study Clinical Trial
The Sygen multicenter acute spinal cord injury study.
Randomized, double-blind, sequential, multicenter clinical trial of two doses of Sygen versus placebo. ⋯ Although not proven in the primary efficacy analysis of this trial, Sygen appears to be beneficial in patients with severe spinal cord injury.
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Randomized Controlled Trial Multicenter Study Comparative Study Clinical Trial
2001 Volvo Award Winner in Clinical Studies: Lumbar fusion versus nonsurgical treatment for chronic low back pain: a multicenter randomized controlled trial from the Swedish Lumbar Spine Study Group.
A randomized controlled multicenter study with a 2-year follow-up by an independent observer. ⋯ Lumbar fusion in a well-informed and selected group of patients with severe CLBP can diminish pain and decrease disability more efficiently than commonly used nonsurgical treatment.
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Randomized Controlled Trial Clinical Trial
Cost effectiveness of periradicular infiltration for sciatica: subgroup analysis of a randomized controlled trial.
A subgroup analysis of a prospective, randomized controlled trial was performed. ⋯ In addition to short-term effectiveness for contained herniations and lesions at L3-L4-L5, steroid treatment also prevented surgery for contained herniations. However, steroid was countereffective for extrusions. The results of the subgroup analyses call for a verification study.