Spine
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This study was designed to investigate the difference of rib length of idiopathic scoliosis using experimentally induced scoliosis by pinealectomy in chickens. ⋯ Our results indicated that rib length was not related to the experimental scoliosis examined in this study. Further study is encouraged to investigate if the asymmetric rib length plays a role in causing or promoting other types of scoliosis, especially in primate or human idiopathic scoliosis.
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Biologic study on the effects of coculture of bovine articular chondrocytes transduced ex vivo with genes expressing bone morphogenetic proteins (BMPs) on nucleus pulposus (NP) cells. ⋯ Bovine NP cells are stimulated to produce proteoglycans and collagen when exposed to chondrocytes transduced with genes for various BMPs. If applied to the treatment of disc degeneration, this strategy could provide the disc with not only metabolically active chondrocytes but also promote matrix replenishment by stimulating native NP cells.
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Comparative Study
Posterior vertebral column resection in fixed lumbosacral deformity.
Retrospective study. ⋯ PVCR is an effective procedure for the management of fixed lumbosacral deformity. It provides satisfactory correction and improved functional outcomes. However, it is a technically demanding and exhausting procedure with possible risks for complications.
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Prospective observational study with a 2- to 3-year follow-up. ⋯ The delayed muscle reflex response significantly increases the odds of sustaining an LBI. These delayed latencies appear to be a preexisting risk factor and not the effect of an LBI.
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Comparative Study
A new stand-alone anterior lumbar interbody fusion device: biomechanical comparison with established fixation techniques.
Established lumbar fixation methods were assessed biomechanically, and a comparison was made with a new stand-alone anterior lumbar interbody cage device incorporating integrated anterior fixation. ⋯ The Test-device alone provided similar and the Test-device and TS higher stability than the pedicle screw constructs evaluated. These results support progression to clinical trials using the Test-device as a stand-alone implant.