Spine
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Review
The effect of relative needle diameter in puncture and sham injection animal models of degeneration.
Biomechanical study and literature review. ⋯ A needle puncture may directly alter mechanical properties via nucleus pulposus depressurization and/or anulus fibrosus damage, depending on the relative needle size. As more basic science research is aimed at treating disc degeneration via injection of therapeutic factors, these findings provide guidance in design of animal studies. Such studies should consider the relative needle size and include sham control groups to account for the potential effects of the needle injection.
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A case report and literature review of Kümmell's disease. ⋯ Only after an extensive workup, including 3 biopsies of the affected area was the diagnosis of Kümmell's disease considered and surgical treatment performed. CONCLUSION.: Delayed vertebral body collapse, i.e., Kümmell's disease, needs to be considered in any patient with recurrent or worsening spinal symptoms. Under-recognition of this condition leads to delayed diagnosis and treatment.