Spine
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In vitro study about angiogenic potentiality of ligamentum flavum (LF) cells using coculture of human lumbar LF cells and activated macropage-like THP-1 cells. ⋯ LF cells interact with macrophage-like cells to produce angiogenesis-related factors except TGF-β1. Activated LF cells that have been exposed to macrophage, can impact the inducement of angiogenesis-related factors, suggesting that fibrosis and scarring during inflammatory reaction is the major pathomechanism of LF hypertrophy.
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A cadaveric biomechanical experiment was conducted to assess the range of motion (ROM) and screw strain at S1 in a long instrumented spinal fusion construct to compare the effects of various surgical strategies for L5-S1 stabilization. ⋯ The results of this study indicated that iliac screws and AxiaLITR provide similar stability at L5-S1, while significantly reducing the strain on the S1 screws.
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Cross-sectional study of teaching general practitioners (TGPs) in the South of France. ⋯ French TGPs believe that CLBP Web sites should focus on nonmedical, practical advice; they consider the design at least as important as the medical information. This viewpoint seems to conflict in part with patients' expectations. Good-quality and interactive Web sites could reduce this discordance. A list of approved sites should be available for general practitioners to recommend to their patients, to supplement information given during the consultation.
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Retrospective cohort study of Medicare claims. ⋯ In this older population having fusion surgery for lumbar stenosis, uptake of BMP was rapid, and greatest among patients with prior surgery or having complex fusion procedures. BMP appeared safe in the perioperative period, with no increase in major medical complications. Use of BMP was associated with greater hospital charges but fewer nursing home discharges, and was not associated with reduced likelihood of reoperation.
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A case report of a patient with adhesive arachnoiditis after combined spinal and epidural anesthesia. ⋯ This is the first report of a patient with a giant AASC and ES caused by spinal and epidural anesthesia. Although the optimal surgical treatment for these conditions remains unclear, shunting of the cyst effectively prevented the progression of symptoms.