Journal of cancer research and clinical oncology
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J. Cancer Res. Clin. Oncol. · Apr 2012
MiR-181d acts as a tumor suppressor in glioma by targeting K-ras and Bcl-2.
Recently, several microRNAs (miRNAs) were reported to be involved in the modulation of glioma development. The aim of our study was to determine the effect of miR-181d on the growth of glioma and to investigate whether this growth is modulated by targeting K-ras and Bcl-2. ⋯ MiR-181d may act as a glioma suppressor by targeting K-ras and Bcl-2.