Journal of cancer research and clinical oncology
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J. Cancer Res. Clin. Oncol. · Jun 2014
Multiple primary tumors following stage II and III rectal cancer in patients receiving radiotherapy, 1998-2010.
This report investigated the impact of radiation therapy among stage II/III rectal cancer patients who were resected for cure and then developed second primary cancer. ⋯ While preoperative radiation therapy is advantageous for reducing rectal cancer recurrence, this study identifies advantages of postoperative radiation for reducing second primary cancers. This research will help improve recommendations for postdiagnosis surveillance in patients with rectal cancer.