Clinical cardiology
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Clinical cardiology · Feb 2011
Randomized Controlled TrialThe effects of statin monotherapy and low-dose statin/ezetimibe on lipoprotein-associated phospholipase A₂.
Many of the pleiotropic effects of statins remain to be elucidated. ⋯ Atorvastatin monotherapy was stronger at reducing plasma Lp-PLA₂ than the low-dose atorvastatin/ezetimibe combination after equivalent LDL-C lowering. This result may provide evidence of potential statin effects beyond the lowering of LDL-C.