Journal of the American Academy of Dermatology
-
J. Am. Acad. Dermatol. · Mar 2015
Randomized Controlled TrialEfficacy and safety of brodalumab in subpopulations of patients with difficult-to-treat moderate-to-severe plaque psoriasis.
Novel therapies are needed for difficult-to-treat populations of patients with psoriasis. ⋯ Brodalumab is efficacious in patients with psoriasis with or without a history of PsA or biologic use.
-
J. Am. Acad. Dermatol. · Mar 2015
Multicenter StudyA prospective study of risk for Sturge-Weber syndrome in children with upper facial port-wine stain.
Upper facial port-wine stain (PWS) is a feature of Sturge-Weber syndrome (SWS). Recent studies suggest that the distribution of the PWS corresponds to genetic mosaicism rather than to trigeminal nerve impairment. ⋯ Specific PWS distribution patterns are associated with an increased risk of SWS. These PWS patterns conform to areas of somatic mosaicism. Terminology stipulating ophthalmic division of trigeminal nerve territory involvement in SWS should be abandoned.
-
J. Am. Acad. Dermatol. · Mar 2015
ReviewA review of traditional and novel oral anticoagulant and antiplatelet therapy for dermatologists and dermatologic surgeons.
Dermatologic surgeons will increasingly encounter patients on novel oral antiplatelet and anticoagulant medications. ⋯ Novel anticoagulant and antiplatelet drugs are revolutionizing therapy for cardiovascular diseases. As these medications become more prevalent, dermatologists and dermatologic surgeons must be mindful of the bleeding risk that will apply in our everyday practices.