Journal of the American Academy of Dermatology
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J. Am. Acad. Dermatol. · Aug 1993
Case ReportsFollicular mycosis fungoides. A clinical and histologic variant of cutaneous T-cell lymphoma: report of two cases.
We report two cases of mycosis fungoides with marked, pleomorphic follicular manifestations. Follicular hyperkeratosis, comedo-like lesions, acquired epidermal cysts, and patchy alopecia developed in various locations in both patients. Findings of histopathologic and immunohistochemical studies showed atypical CD4+ T lymphocytes infiltrating the follicles without follicular mucinosis. ⋯ These findings suggest that the follicular lesions were specific for mycosis fungoides. These manifestations represent a distinct clinical and histologic form of mycosis fungoides. This variant probably accounts for cases of mycosis fungoides with clinically suspected alopecia mucinosa in which follicular mucinosis cannot be histologically proved.
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J. Am. Acad. Dermatol. · Mar 1993
Planimetric rate of healing in venous ulcers of the leg treated with pressure bandage and hydrocolloid dressing.
Venous leg ulcers are a common cause of morbidity, but few predictive parameters exist that can be used to follow their progress. ⋯ The initial healing rate (delta A/p(0-4)) may be an appropriate end point for clinical investigations comparing therapies for the treatment of chronic venous leg ulcers.
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J. Am. Acad. Dermatol. · Feb 1993
Review Case ReportsExtensive cutaneous hyperpigmentation caused by minocycline.
A 65-year-old man had cutaneous hyperpigmentation that had occurred over the previous 2 1/2 years. The hyperpigmentation was extensive and involved the sclerae, nail beds, and total body; the palms and buttocks were spared. ⋯ A careful history showed that minocycline was the cause. Its use was discontinued, and after several years the patient's pigmentation is gradually returning to normal.
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J. Am. Acad. Dermatol. · Feb 1993
Diagnostic significance of nailfold bleeding in scleroderma spectrum disorders.
The early detection of scleroderma spectrum disorders (SSD) is important. ⋯ The presence of nailfold bleeding is useful for the early detection of SSD.
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J. Am. Acad. Dermatol. · Jan 1993
Case ReportsCutaneous vasculitis in the newborn of a mother with cutaneous polyarteritis nodosa.
Vasculitis in an infant of a woman who had a long history of cutaneous polyarteritis nodosa is reported. During the neonatal period the child developed cutaneous vasculitis manifested by livedo reticularis, cutaneous nodules, and acral necrosis. The infant's vasculitis remitted by age 7 months. This is the third such report and strongly suggests the presence of a circulating factor that is capable of crossing the placenta and inducing cutaneous polyarteritis nodosa.