Medicine and science in sports and exercise
-
Med Sci Sports Exerc · Apr 2021
Multicenter StudySleep, Sedentary Behavior, Physical Activity, and Cardiovascular Health: MESA.
Sleep, sedentary behavior, and physical activity are each independently associated with cardiovascular health (CVH). It is unknown how substituting time in sedentary behavior with sleep or physical activity affects overall CVH. ⋯ Sleep, LIPA, and MVPA are all associated with more favorable overall CVH and several key risk factors for cardiovascular disease. These findings underscore the importance of lifestyle modifications in improving CVH.
-
Med Sci Sports Exerc · Sep 2012
Randomized Controlled Trial Multicenter StudyEfficacy and safety of diclofenac diethylamine 2.32% gel in acute ankle sprain.
Topical diclofenac diethylamine (DDEA) 2.32% gel achieves lasting efficacy in localized pain with two applications per day, while maintaining the favorable safety profile of topical diclofenac and potentially improving convenience and patient compliance. ⋯ DDEA 2.32% gel twice daily (applied in the morning and evening) was well tolerated and provided lasting relief from pain, improved function, and reduced symptomatic healing time in uncomplicated ankle sprain.