Journal of tropical pediatrics
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Randomized Controlled Trial Comparative Study
A pilot study of comparison of BCPAP vs. VCPAP in preterm infants with early onset respiratory distress.
Bubble continuous positive airway pressure (BCPAP) is a low-cost nasal CPAP delivery system with potential benefits for developing nations. The objective of the study was to compare the efficacy and safety of BCPAP with ventilator CPAP (VCPAP) in preterm neonates with moderate respiratory distress. ⋯ BCPAP appears to be a promising method of CPAP delivery in preterm neonates with moderate respiratory distress.
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Vitamin D deficiency can develop very early in infancy, and be characterized by severe hypocalcemic symptoms. This study was done to determine the relation between symptomatic hypocalcemia and vitamin D deficiency in newborn infants and their mothers in the state of Qatar. This is a retrospective study for all newborns presented to the Pediatric Emergency Centers in Qatar with symptomatic hypocalcemia from 1 January 2006 to 31 December 2007. ⋯ Vitamin D deficiency with or without relative hypoparathyroidism was the attributed cause. Vitamin D deficiency in newborn infants secondary to maternal vitamin D deficiency leading to hypocalcemic symptoms is not uncommon in the state of Qatar. Therefore, vitamin D supplementation in pregnant and lactating mothers in the state of Qatar should be considered after proper screening.
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Case Reports
Hypokalemic paralysis following severe vomiting in a child with intestinal obstruction due to round worms.
Ascariasis is one of the most common helminthic infestations in humans. Massive infestation can give rise to serious complications such as intestinal obstruction. We present a 4-year-old boy, who presented with acute flaccid quadriparesis due to the hypokalemic alkalosis induced by severe vomiting. Severe vomiting was due to intestinal obstruction caused by round worms.
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To determine incidence, related factors, outcome, bacterial organisms and their sensitivity patterns with regard to ventilator-associated pneumonia (VAP) in children. ⋯ Use of H(2) blockers (Ranitidne) is associated with higher incidence of VAP in children.
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Randomized Controlled Trial
Dose-dependent effect of Lactobacillus rhamnosus on quantitative reduction of faecal rotavirus shedding in children.
Beneficial effects of probiotics in acute infectious diarrhoea in children are mainly seen in watery diarrhoea and viral gastroenteritis. Lactobacillus rhamnosus, one the most extensively studied probiotic strains, is effective in shortening courses of acute diarrhoea in children. However, the dose-dependent effect of Lactobacillus upon quantification of faecal rotavirus shedding in humans remains little known. ⋯ However, the high-dose group had a significant reduction of faecal rotavirus concentration (64.2 x 10(5) particles/ml vs. 9.0 x 10(5) particles/ml, p = 0.012). Without any exception, the faecal rotavirus concentrations of all eight patients in the high-dose Lcr35 group declined by 86% after 3 days when compared with those before Lcr35 administration. In conclusion, this is the first report to provide quantitative evidence of the dose-dependent effect of Lactobacillus rhamnosus, a minimal effective dose of 6 x 10(8) CFU for 3 days, upon the faecal rotavirus shedding in paediatric patients.