Anticancer research
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Anticancer research · Apr 2019
Characterization of Bone Lesions in Myeloma Before and During Anticancer Therapy Using 18F-FDG-PET/CT and 18F-NaF-PET/CT.
The objective of this study was to characterize tumor activity and mineralization status in newly-detected multiple myeloma (MM) bone lesions using 2-18F-fluoro-2-deoxy-D-glucose (18F-FDG)-PET/CT and 18F-sodium fluoride (18F-NaF)-PET/CT before and after antitumor treatment. ⋯ Based on our data, antitumor therapy in MM reduces not only tumor activity, but also the mineralization status of bone lesions. A second follow-up scan in a subset of the cohort yielded no change in mineralization status.