Cephalalgia : an international journal of headache
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Prior studies demonstrate reduced cortical thickness and volume in migraineurs. However, the effect of age on cortical thickness has not been assessed in migraineurs. In this study we investigated whether the process of aging on cortical thickness affects migraineurs differently compared to age-matched healthy controls, i.e. whether aging exacerbates cortical thinning in migraineurs. ⋯ Results suggest that migraine is associated with atypical cortical aging, suggesting that the migraine disease process interacts with aging to affect cortical integrity.
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There is a strong association between migraine and depression. The aim of this study is to identify migraine-specific factors involved in this association. ⋯ This study identified allodynia, in addition to high migraine attack frequency, as a new migraine-specific factor associated with depression.