Klinische Pädiatrie
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Klinische Pädiatrie · Mar 1994
Case Reports[Successful treatment of therapy refractory shock lung in a newborn infant with congenital varicella using extracorporeal membrane oxygenation].
A newborn with congenital varicella complicated by varicella pneumonia was transferred to our hospital on day 16 of life for the consideration of extracorporeal membrane oxygenation (ECMO). The newborn received varicella zoster immunoglobulin 13 hours after birth since the mother developed a varicella exanthema two days before delivery. On day 10 of life the newborn became clinically symptomatic with red macules and pustules. ⋯ ECMO was initiated in the veno-arterial mode on day 17 due to severe respiratory failure despite maximal conventional assisted ventilation and carried out for 14 days. With the age of 10 weeks he was discharged from the hospital with mild chronic lung disease without oxygen requirements and without neurological handicap. ECMO might be considered as life saving support in newborns with severe congenital varicella, considered to have a high mortality risk.
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Klinische Pädiatrie · Mar 1994
Comparative Study[Measuring cardiac output in infants with the Fick principle via oxygen consumption: animal experiment and clinical results].
The aim of this investigation was the validation of cardiac output measurement in children using the method of Fick with the help of a new equipment for the determination of oxygen uptake. ⋯ The animal model showed a good correlation of cardiac output measurement on thermodilution and on Fick's method (alpha = 0.001, t-test of significance of correlation). With the method of Fick we found also reliable results at follow up in the clinical routine in the 5 children. The comparison of cardiac output calculated with the central venous oxygen content versus the pulmonary-arterial oxygen content shows a good correlation over all (r = 0.92). In some cases however we found profound differences.