Klinische Pädiatrie
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Klinische Pädiatrie · Jan 2010
Case Reports[Spontaneously occurring pneumomediastinum related to a pneumopericardium, a pneumothorax and a skin emphysema in a 12-year old boy].
The spontaneous pneumomediastinum describes the existence of air inside the mediastinum, is caused by an alveolar rupture in most cases and occurs without influence of traumata, surgery or iatrogen interferences. This is a rare and, in most cases, benign disease. An association between a pneumomediastinum, a pneumopericardium, a pneumothorax, as well as a skin emphysema, is extremely rare in children and young adults. ⋯ In this case report and literature review possible causes, differential diagnoses, and treatments are summarized. Based on this, we suggest that this case report serve as a diagnostic guide for patients presenting with these symptoms.
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Klinische Pädiatrie · Jan 2010
Multicenter Study Comparative Study Controlled Clinical TrialSurfactant without intubation in preterm infants with respiratory distress: first multi-center data.
Recently in a report of a single center a method has been described to apply surfactant via a thin endotracheal catheter to very low birth weight infants spontaneously breathing with nasal continuous positive airway pressure. We now analyzed available multicenter data. ⋯ A new method of surfactant application was associated with a lower prevalence of mechanical ventilation and better pulmonary outcome. A prospective controlled trial is required to determine whether this approach is superior to standard care.