Journal of the American College of Cardiology
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J. Am. Coll. Cardiol. · Jan 2008
Impact of impaired fasting glucose on cardiovascular disease: the Framingham Heart Study.
We sought to determine whether impaired fasting glucose (IFG) predicts cardiovascular disease (CVD) events. ⋯ In women, both IFG definitions were associated with increased CHD risk, whereas neither IFG definition identified men at increased short-term risk for CHD or CVD. The finding that women with FPG 110 to 125 mg/dl had similar CHD risk compared with women with diabetes suggests that CHD risk in women may be elevated at a lower glucose level than for men.
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J. Am. Coll. Cardiol. · Jan 2008
Multicenter StudyShort- and long-term prognosis of syncope, risk factors, and role of hospital admission: results from the STePS (Short-Term Prognosis of Syncope) study.
We sought to assess short- and long-term prognosis of syncope and associated risk factors. ⋯ Risk factors for short- and long-term adverse outcomes after syncope differed. Hospital admission favorably influenced syncope short term prognosis. Instead, 1-year mortality was unaffected by hospital admission and related to comorbidity.
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J. Am. Coll. Cardiol. · Jan 2008
Elevated intra-abdominal pressure in acute decompensated heart failure: a potential contributor to worsening renal function?
This study sought to determine whether changes in intra-abdominal pressure (IAP) with aggressive diuretic or vasodilator therapy are associated with improvement in renal function in acute decompensated heart failure (ADHF). ⋯ Elevated IAP is prevalent in patients with ADHF and is associated with impaired renal function. In the setting of intensive medical therapy for ADHF, changes in IAP were better correlated with changes in renal function than any hemodynamic variable.
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J. Am. Coll. Cardiol. · Jan 2008
Randomized Controlled Trial Comparative StudyEffect of intravenous iron sucrose on exercise tolerance in anemic and nonanemic patients with symptomatic chronic heart failure and iron deficiency FERRIC-HF: a randomized, controlled, observer-blinded trial.
We tested the hypothesis that intravenous iron improves exercise tolerance in anemic and nonanemic patients with symptomatic chronic heart failure (CHF) and iron deficiency. ⋯ Intravenous iron loading improved exercise capacity and symptoms in patients with CHF and evidence of abnormal iron metabolism. Benefits were more evident in anemic patients. (Effect of Intravenous Ferrous Sucrose on Exercise Capacity in Chronic Heart Failure; http://www.clinicaltrials.gov/ct/show/NCT00125996; NCT00125996).