Journal of the American College of Cardiology
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J. Am. Coll. Cardiol. · Oct 1992
Case Reports Clinical TrialEfficacy and safety of propafenone in congenital junctional ectopic tachycardia.
Class IC antiarrhythmic drugs have recently been shown to be effective in some patients with atrial ectopic tachycardia. We therefore studied the efficacy of these drugs in patients with congenital junctional ectopic tachycardia. ⋯ Because of its effectiveness, safety and lack of side effects, propafenone appears to be a valuable drug in the treatment of junctional ectopic tachycardia in newborns and infants.
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J. Am. Coll. Cardiol. · Oct 1992
Hemodynamic and volume correlates of left ventricular diastolic relaxation and filling in patients with aortic stenosis.
The aim of the present study was to evaluate the hemodynamic and volume correlates of early diastolic filling and isovolumetric relaxation in patients with aortic stenosis. ⋯ In patients with aortic stenosis, left ventricular filling is essentially determined by left atrial pressure, whereas isovolumetric relaxation more closely depends on the severity of muscle hypertrophy and chamber dilation.
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J. Am. Coll. Cardiol. · Oct 1992
Comparative StudyLong-term results of percutaneous aortic valvuloplasty compared with aortic valve replacement in patients more than 75 years old.
To assess the long-term results of percutaneous aortic valvuloplasty and aortic valve replacement in elderly persons, two similar nonrandomized series of patients greater than or equal to 75 years old treated by one or the other method between January 1986 and March 1989 in the same institution were compared. ⋯ The results of percutaneous aortic valvuloplasty do not compare favorably with those of surgery in elderly people, and this treatment should not be recommended.
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J. Am. Coll. Cardiol. · Sep 1992
Randomized Controlled Trial Clinical TrialAntiarrhythmic drug therapy and cardiac mortality in atrial fibrillation. The Stroke Prevention in Atrial Fibrillation Investigators.
The relation between cardiac mortality and antiarrhythmic drug administration has not been fully determined. This relation was analyzed in 1,330 patients enrolled in the Stroke Prevention in Atrial Fibrillation Study, a randomized clinical trial comparing warfarin, aspirin and placebo for the prevention of ischemic stroke or systemic embolism in patients with nonvalvular atrial fibrillation. ⋯ Although antiarrhythmic drug therapy was not randomly determined in this trial, the data suggest that in patients with atrial fibrillation and a history of congestive heart failure, the risk of such therapy may outweigh the potential benefit of maintaining sinus rhythm.
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J. Am. Coll. Cardiol. · Sep 1992
Intraoperative evaluation of mitral valve regurgitation and repair by transesophageal echocardiography: incidence and significance of systolic anterior motion.
This study was designed to delineate the utility and results of intraoperative transesophageal echocardiography in the evaluation of patients undergoing mitral valve repair for mitral regurgitation. ⋯ Transesophageal echocardiography is a valuable adjunct in the intraoperative assessment of mitral valve repair.