Diagnostic microbiology and infectious disease
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Diagn. Microbiol. Infect. Dis. · Nov 2020
Monitoring antibody response following SARS-CoV-2 infection: diagnostic efficiency of 4 automated immunoassays.
SARS-CoV-2 seroconversion is important for epidemiological studies as well as contact tracing. ⋯ The Elecsys and the VIDAS methods with a combination of IgG/IgM measurement demonstrated a high sensitivity with no false positive results.
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Diagn. Microbiol. Infect. Dis. · Nov 2020
False-positive SARS-CoV-2 serology in 3 children with Kawasaki disease.
Kawasaki disease (KD) is an acute febrile and eruptive disease with systemic vasculitis predominantly affecting young East Asian children. Recent reports showed that children with KD-like disease from KD low prevalence regions had positive SARS-CoV-2 serology despite a negative SARS-CoV-2 polymerase chain reaction (PCR) in respiratory samples. ⋯ Detection of neutralizing antibodies is recommended to confirm previous SARS-CoV-2 infection in IgG-positive but PCR-negative patients.