Journal of hypertension
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Journal of hypertension · Nov 2012
Association between hypertension and musculoskeletal complaints: a population-based study.
To investigate the association between hypertension and musculoskeletal complaints among men and women selected by a population-based sample. ⋯ Chronic musculoskeletal complaints are more frequent in men with uncontrolled hypertension under drug treatment. The absence of association in women and in hypertensive men not taking BP drugs suggest that hypertension is not a risk or protection against musculoskeletal complaints.
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Journal of hypertension · Aug 2012
Randomized Controlled Trial Comparative StudySequential nephron blockade versus sequential renin-angiotensin system blockade in resistant hypertension: a prospective, randomized, open blinded endpoint study.
To compare two drug regimens to treat resistant hypertension. ⋯ In patients with resistant hypertension, sequential nephron blockade induces a large and well tolerated reduction in blood pressure via a progressive increase in sodium depletion, and is more effective than sequential renin-angiotensin system blockade.
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Journal of hypertension · Aug 2012
Visit-to-visit blood pressure variations: new independent determinants for cognitive function in the elderly at high risk of cardiovascular disease.
Recently, visit-to-visit blood pressure (BP) variability has been shown to be associated with silent cerebral injury and stroke. However, the relationships between visit-to-visit BP variation and cognitive function are not clear. ⋯ In the high-risk elderly, exaggerated visit-to-visit BP fluctuations were significant indicators for cognitive impairment.
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Journal of hypertension · Aug 2012
Vitamin D status partly explains ethnic differences in blood pressure: the 'Surinamese in the Netherlands: study on ethnicity and health'.
To investigate the role of vitamin D in explaining ethnic differences in blood pressure among three ethnic groups in the Netherlands (ethnic Dutch, African Surinamese, and south Asian Surinamese). ⋯ Higher blood pressures and higher hypertension risk in south Asian Surinamese and African Surinamese were partly explained by their poorer vitamin D status. However, even after adjustment, significant ethnic blood pressure differences persisted.
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Journal of hypertension · Jul 2012
Randomized Controlled TrialThe velocity of antihypertensive effect of losartan/hydrochlorothiazide and angiotensin II receptor blocker.
The hypotensive effect and the time to attain the maximum antihypertensive effect (stabilization time) of losartan/hydrochlorothiazide (HCTZ) combination therapy and therapy with a maximal dose of angiotensin II receptor blockers (ARBs) in patients who failed to achieve adequate blood pressure (BP) control on a medium-dose of ARBs were compared by analyzing exponential decay functions using daily serial morning home BP measurements. ⋯ Changing from a medium dose of ARB monotherapy to combination therapy was more effective in the reduction of home SBP and achieved goal BP more rapidly than increasing the ARB dose. Home BP measurement is a useful tool for characterizing the antihypertensive effects of drugs.