European journal of anaesthesiology
-
Clinical Trial
Changes in jugular bulb oxygenation in patients undergoing warm coronary artery bypass surgery (34-37 degrees C).
Imbalance between cerebral oxygen supply and demand is thought to play an important role in the development of cerebral injury during cardiac surgery with cardiopulmonary bypass. ⋯ We found that jugular bulb oxygen saturation, jugular bulb oxygen tension and oxygen extraction ratio are mainly dependent on arterial carbon dioxide tension, and arterial-jugular bulb oxygen content difference is dependent on arterial carbon dioxide tension and the bypass temperature. Our results suggest jugular bulb oxygenation is mainly dependent on arterial carbon dioxide tension during warm cardiopulmonary bypass.
-
Randomized Controlled Trial Clinical Trial
Small doses of remifentanil or sufentanil for blunting cardiovascular changes induced by tracheal intubation: a double-blind comparison.
To compare the effects on cardiovascular changes induced by tracheal intubation when small doses of either remifentanil or sufentanil are used in the presence of midazolam. ⋯ In healthy normotensive patients without cardiovascular disease the use of a relatively small dose of either remifentanil or sufentanil after standard midazolam premedication results in a similar and clinically acceptable effectiveness in blunting the cardiovascular changes induced by tracheal intubation.
-
Randomized Controlled Trial Clinical Trial
Intravenous ketamine attenuates arterial pressure changes during the induction of anaesthesia with propofol.
To investigate whether the administration of ketamine before induction with propofol produces a smaller decrease in arterial pressure. ⋯ Administration of ketamine before induction with propofol preserved haemodynamic stability compared with induction with propofol alone.
-
Clinical Trial
The plasma elimination rate and urinary secretion of procalcitonin in patients with normal and impaired renal function.
The amount of procalcitonin eliminated in the urine and the plasma disappearance rate of procalcitonin were evaluated in patients with normal and impaired renal function, because patients with sepsis are a main target group for procalcitonin measurement, and these patients often develop renal dysfunction. ⋯ Renal elimination of procalcitonin is not a major mechanism for procalcitonin removal from the plasma. Although the plasma disappearance rate may be prolonged up to 30-50% in some patients with renal dysfunction, clinical diagnostic decisions may not be severely influenced by this moderate prolongation of procalcitonin elimination. We conclude that procalcitonin can be used diagnostically in patients with renal failure as well as in those with normal renal function.
-
Comment Letter
Use of 10% lidocaine in the cuff of the endotracheal tube.