Journal of perinatology : official journal of the California Perinatal Association
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A case history of a fatal neonatal infection caused by Salmonella enteritidis group D is reported. The baby deteriorated rapidly at 24 hours after birth with clinical signs and symptoms of an acute abdomen. ⋯ The same organism was found in cultures taken from stool and vaginal swabs from the mother. This clearly confirmed transmission of the infection during delivery.
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Clinical Trial Controlled Clinical Trial
Ibuprofen use to reduce the incidence and severity of bronchopulmonary dysplasia: a pilot study.
To assess the safety and efficacy of ibuprofen in reducing the incidence and severity of bronchopulmonary dysplasia (BPD) in preterm infants. ⋯ Although a trend toward less ventilator and hospital days in the ibuprofen group was observed in this pilot study, the differences were not statistically significant. The incidence of BPD was similar in both groups. In the study group, two infants developed gastrointestinal complications and a third infant experienced reversible renal failure. The plasma ibuprofen levels were low. Further studies are needed to assess the use of ibuprofen for the prevention and/or treatment of BPD in preterm infants.